643 Grand Avenue
SouthSanFrancisco, CA 94080
$998,888
Open Houses
Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging and an additional 2 car off street parking in front of the house. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.
| Listing Id: | ML82059314 |
|---|---|
| List Price: | $998,888 |
| Listing Class: | Residential |
| Subclass: | SingleFamilyResidence |
| Listing Status: | Active |
| Bedrooms: | 3 |
| Number Of Full Bathrooms : | 4 |
| Living Sq Ft: | 1,630 |
| Lot Size Sq Ft County: | 3,500.0 |
| City Name: | SouthSanFrancisco |
| County Name: | Sanmateo |
| Postal Code: | 94080 |
| Year Built: | 1895 |
| Area: | Old South Sf Rocca |
| Basement: | No |
| Cooling: | None |
| Cross Street: | Orange Avenue |
| Elementary School District: | SouthSanFranciscoUnified |
| Flooring: | Hardwood |
| Garage Spaces: | 2.0 |
| Heating: | CentralForcedAir |
| High School District: | SouthSanFranciscoUnified |
| Lot Size Source: | Assessor |
| No Of Stories: | 2 |
| Parking Spaces: | 2 |
| Roof: | Shingle |
| State Or Province Name: | CA |
| Utilities : | PublicUtilities, WaterPublic |
| Year Built Source: | Assessor |
| Building Area Total: | 1630.0 |
| Lot Size Area: | 3,500.0 |
| Original List Price: | $1,248,000 |
| Garage?: | Yes |
| Listing Contract Date: | 2026-08-27 |
| Parcel Number: | 012-241-120 |
| Room Bathroom Features: | FullonGroundFloor |
| Room Bedroom Features: | PrimaryBedroomonGroundFloor |
| Room Dining Room Features: | DiningAreainLivingRoom |
| Room Family Room Features: | NoFamilyRoom |
| Walk Score: | 82 |
| Year Built Details: | 2 |
| Zoning: | RM0000 |
| Appliances: | Dishwasher, GarbageDisposal, Refrigerator, WasherDryer, WaterSoftener |
| Building Area Source: | Assessor |
| Lot Size Units: | SquareFeet |
| Status: | Active |
| Postal City: | SouthSanFrancisco |
| Foundation Details: | Slab |
| Gas: | PublicUtilities |
| Interior Features: | OneOrMoreSkylights, WalkinCloset |
| Parking Features: | Detached, OnStreet |
| Sewer: | PublicSewer |
| Special Listing Conditions: | Standard |
| Water Source: | Public |
Listing Courtesy of: Christie's International Real Estate Sereno
Listing Agent: Jill Penna
415-244-8630
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Property Last Updated: October 08, 2026 04:56 PM - ET
